Global Quantification Exposes Abundant Low-Level Off-Target Activity by Base Editors

Time: 1:40 pm
day: Day One


  • Discovering how much of the off-target activity of the deaminases are non-specific
  • Discussing a new class of off-target events that are invincible to the established methods for detection of genomic variations and were thus far overlooked
  • Divulging a computational tool to quantify global off-target activity, which can be used to optimise future base editors