Global Quantification Exposes Abundant Low-Level Off-Target Activity by Base Editors
Time: 1:40 pm
day: Day One
Details:
- Discovering how much of the off-target activity of the deaminases are non-specific
- Discussing a new class of off-target events that are invincible to the established methods for detection of genomic variations and were thus far overlooked
- Divulging a computational tool to quantify global off-target activity, which can be used to optimise future base editors
