Harnessing Endogenous ADAR for Oligo-Directed RNA Editing

• The OPERA platform (Oligonucleotide Promoted Editing of RNA), which utilizes synthetic oligonucleotides that recruit ADARs to repair disease-causing mutations at the RNA level

• In addition to repairing standard G-to-A mutations, our platform enables the modulation of protein function by changing the amino acid code

• Updates on the OPERA platform and progress towards the clinic

Speakers:

Maryam Habibian

Director, Head of Medicinal Chemistry

Korro Bio