Adrian Briggs

Adrian Briggs

Company: Shape Therapeutics

Job title: Head of Platform Technologies


RNAfix: Therapeutic RNA Editing with Engineered Guide RNAs and Endogenous ADAR 9:40 am

Understanding endogenous ADAR enzyme can be harnessed to edit adenosines in RNA and treat disease. A massively parallel screen of guide RNAs (gRNAs) identifies designs that enable highly efficient and specific editing of clinically relevant targets Divulging that machine learning analysis of deep gRNA screening datasets allows computational generation of gRNAs with improved performance relative…Read more

day: Day One

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