Conference Day Two

8:00 am Morning Coffee & Light Breakfast

8:50 am Chair’s Opening Remarks

• Mao Taketani Director, Synthetic Biology, Jorna Therapeutics

Highlighting Strategies for Optimizing RNA Editing Therapeutics to Effectively Treat a Wide Landscape of Genetic Diseases

9:00 am Unlocking the Edit-Verse: Combining Machine Learning & Multiple AIMer Applications to Build a High-Impact RNA Editing Pipeline

• Kenneth Longo Vice President - Discovery Data Science, Wave Life Sciences
• Ginnie (Hsiu-Chiung) Yang Senior Vice President - Translational Medicine, Wave Life Sciences

9:30 am Wobble Base Pairs Enable Site-Directed RNA Base Editing with High Efficiency & Precision in-vivo

• Philipp Reautschnig Academic Researcher, University of Tuebingen

10:00 am Morning Break & Networking

Addressing Challenges of Durability to Achieve More Effective Therapeutics for Treating Rare Diseases

11:00 am Roundtable Discussion: Discussing Strategies for Improved Longevity of Editing Therapeutics to Achieve More Durable Effects

• Venkata Krishnamurthy Senior Vice President & Head of Platform & RNA Editing, Korro Bio

12:00 pm Lunch & Networking

Uncovering Brand-New Data Updates for Progression Towards the Clinic & Accelerating Development of RNA Editors

1:00 pm RestorAATion: First Clinical Progam Evaluating an RNA Editing Therapeutics in Humans

• Cynthia Caracta Executive Medical Director, Wave Life Sciences

1:30 pm Edit the Message: Rewrite the Future

• Venkata Krishnamurthy Senior Vice President & Head of Platform & RNA Editing, Korro Bio

2:00 pm Developing Axiomer RNA Editing Technology Towards Clinical Development

• Lenka van Sint Fiet Senior Director Platform, ProQR Therapeutics

2:30 pm Afternoon Break & Networking

Identifying New Applications of RNA Editing to Unleash its Full Potential for Accelerated Treatment of More Widespread Disease

3:30 pm RADAR: An ADAR-Based Technology for Selective Translation of Therapeutic Proteins

• Eerik Kaseniit, PhD Chief Scientific Officer & Co-Founder, Radar Therapeutics

4:00 pm Engineering gRNA-Free Single Enzymes for Programmable RNA Base Editing RNA

• Eerik Kaseniit, PhD Chief Scientific Officer & Co-Founder, Radar Therapeutics
• Zeneng Wang Chair Professor, School of Life Science, Southern University of Science & Technology, Shenzhen, China

4:30 pm miRNA-Based Logic Circuits Encoded on Self-Amplifying RNA for Highly Specific Cancer Cell Classification

• Ron Weiss Professor, Massachusetts Institute of Technology

5:00 pm Chair’s Closing Remarks & End of 5th RNA Editing Summit 2024

• Mao Taketani Director, Synthetic Biology, Jorna Therapeutics